Evaluation of the Relationship Between Aquaporin-1, Hepcidin, Zinc, Copper, and İron Levels and Oxidative Stress in the Serum of Critically Ill Patients with COVID-19Article Published on 2022-12-012022-11-16 Journal: Biological trace element research [Category] COVID19(2023년), SARS, 치료기술, [키워드] antioxidant aquaporin both groups chronic disease control group copper correlation COVID-19 COVID-19 disease COVID-19 patient COVID-19 patients determine disease severity elements Endotracheal intubation had no healthy hepcidin Ill in viral indicated individual Infection Inpatient intensive care Invasive mechanical ventilation Level negative PCR test oxidative stress parameter patients with COVID-19 relationship Result SARS-CoV-2 separated sera Significant statistically significant TAC the healthy the patient Total Total antioxidant status Total oxidant status trace Trace element Trace elements. two groups with COVID-19 Zinc [DOI] 10.1007/s12011-022-03400-6 PMC 바로가기
Low BALF CD4 T cells count is associated with extubation failure and mortality in critically ill covid-19 pneumonia낮은 BALF CD4 T 세포 수는 중환자의 covid-19 폐렴에서 발관 실패 및 사망률과 관련이 있습니다Article Published on 2022-12-012022-09-11 Journal: Annals of Medicine [Category] 바이오마커, 진단, [키워드] affected alveolar alveolar macrophage analysed average BALF BALF CD4 T-cells count baseline Biomarker bivariate analysis Bronchoalveolar lavage fluid caspase caspase-3 cause CD4 CD4 T cell CD4 T-cell Characteristics clinical Clinical characteristics conducted COVID-19 COVID-19 patients COVID-19 pneumonia COVID-19 pneumonia patient COVID-19 pneumonia patients Critically ill critically ill COVID-19 patients Critically ill COVID-19 pneumonia D-dimer D-dimer level eight enrolled extubation failure. groups help IL-17 IL-6 immunopathology IMPROVE Indonesia intubation Invasive mechanical ventilation Laboratory lung Macrophage material Mortality no significant difference no significant differences outcome Patient performed Pneumonia profile Referral reported right lung severe pneumonia severity significant differences significantly survived T-cells Tertiary Tregs understanding was performed were measured [DOI] 10.1080/07853890.2022.2095012 PMC 바로가기 [Article Type] Article
Dysphagia and mechanical ventilation in SARS-COV-2 pneumonia: It’s realObservational Study Published on 2022-12-012023-07-07 Journal: Clinical nutrition (Edinburgh, Scotland) [Category] COVID19(2023년), [키워드] Dysphagia Intensive care medicine Invasive mechanical ventilation SARS-CoV-2 pneumonia Viscosity volume swallowing test (V-VST). [DOI] 10.1016/j.clnu.2021.11.018 PMC 바로가기 [Article Type] Observational Study
Fungal colonization and infections in patients with COVID-19 in intensive care units: A real-life experience at a tertiary-care hospitalResearch article Published on 2022-11-012022-10-05 Journal: Respiratory medicine and research [Category] 진단, [키워드] age antifungal therapy Antifungal treatment Candida albican Candida albicans Computed tomography COVID-19 COVID-19 diagnosis COVID-19-associated pulmonary aspergillosis cross-contamination diagnostic evaluate exhibited Fatality rate fungal Fungal colonization Fungal infection highlight hospital ICU ICUs Infection intensive care intensive care unit Invasive mechanical ventilation laboratory data management mechanical ventilation medical records men outcome pandemic Patient patients patients with COVID-19 performed problem Result risk Risk factors the patient Thorax women [DOI] 10.1016/j.resmer.2022.100937 [Article Type] Research article
Mid-term pulmonary sequelae after hospitalisation for COVID-19: The French SISCOVID cohortResearch article Published on 2022-11-012022-10-05 Journal: Respiratory medicine and research [Category] 임상, [키워드] age Chest computed tomography clinical examination Clinical features Cohort complications consequence COVID-19 CT-scan described diffusing discharge Dyspnoea evaluated Follow-up French functional hospital discharge hospitalisation hospitalised ICU impairment Improved independent risk factor intensive care Invasive mechanical ventilation lung lung capacity Lung function mMRC multicentre nasal non-invasive ventilation observational study outcome Pathogenesis Patient Patient discharge Pneumonia Pulmonary function tests radiological Result sequelae severe COVID-19 significantly more therapeutic option ventilatory [DOI] 10.1016/j.resmer.2022.100933 [Article Type] Research article
Efficacy and safety of nitazoxanide in treating SARS-CoV-2 infection: a systematic review and meta-analysis of blinded, placebo-controlled, randomized clinical trialsArticle Published on 2022-11-012022-11-15 Journal: European Journal of Clinical Pharmacology [Category] SARS, 치료제, [키워드] 95% CI 95% confidence interval addition anti-inflammatory effect antiparasitic antiviral activity blinded clinical benefit continuous variable COVID-19 D-dimer D-dimer level death dichotomous variable Disease progression Effect effect size Efficacy and safety element eligibility enrolled Evidence Frequency ICU admission in vitro individual Inflammation Invasive mechanical ventilation lactate dehydrogenase LDH magnitude Meta-analysis Mild moderate Moderate COVID-19 nitazoxanide no difference Patient patients peer-reviewed performed Placebo placebo-controlled positive positive RT-PCR Primary outcome randomized clinical trial RCT RCTs receiving reducing reduction in reported risk SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infection. secondary outcome serum biomarker SMD standardized mean difference systematic review tested to define treat treated Viral load WBC were used White blood cell with COVID-19 [DOI] 10.1007/s00228-022-03380-5 PMC 바로가기
Vitamin D deficiency is Associated with Increased Risk of Delirium and Mortality among Critically Ill, Elderly Covid-19 PatientsResearch article Published on 2022-11-012022-10-05 Journal: Complementary therapies in medicine [Category] COVID19(2023년), SARS, 바이오마커, [키워드] adjusted association baseline blood pressure collected data Comorbidities confounders coronavirus disease COVID-19 COVID-19 mortality COVID-19 patients Critically ill deficiency delirium demographic characteristics elderly Elderly patient Face mask higher risk Hospital admission Hospitalization Hospitalized ICU ICU admission Ill IMV incidence increase in Increased increased risk information intensive care Invasive mechanical ventilation Laboratory parameters less lower risk mechanical ventilation medications Mortality Older Organ failure outcome Patient positive prevalent propofol Prospective Study Result risk SARS-CoV-2 serum single center Study participants Treatment Vitamin D vitamin D deficiency vitamin D level vitamin D sufficiency was done were recorded [DOI] 10.1016/j.ctim.2022.102855 [Article Type] Research article
Sex differences in determinants of COVID-19 severe outcomes – findings from the National COVID Cohort Collaborative (N3C)Article Published on 2022-10-122022-11-15 Journal: BMC Infectious Diseases [Category] 바이오마커, [키워드] absolute lymphocyte absolute neutrophil adjusted adjusted odds ratio Admission age Analysis association averaged Biomarker Biomarkers both sexes CCI Charlson Comorbidity Index comorbid condition Comorbidities Comorbidity components COVID COVID-19 COVID-19 severity CRP death death rate defined determinant disease Elevation examined ferritin Health highlight hospital Hospitalized IMV Inflammation inflammatory biomarkers Invasive mechanical ventilation lab value Liver disease Logistic regression LOS lymphocytopenia magnitude male medication men men and women moderate to severe Mortality Myocardial infarction N-terminal neutrophil outcome Patient peptide Platelet Platelets predictor previous study Primary outcome procalcitonin Protein remained renal Research retrospective cohort risk risk factor risk of death secondary outcome Sex Sex difference sex differences. significantly solid tumor with COVID-19 women [DOI] 10.1186/s12879-022-07776-7 PMC 바로가기
Real-world effectiveness of molnupiravir and nirmatrelvir plus ritonavir against mortality, hospitalisation, and in-hospital outcomes among community-dwelling, ambulatory patients with confirmed SARS-CoV-2 infection during the omicron wave in Hong Kong: an observational studyArticle Published on 2022-10-082022-11-15 Journal: Lancet (London, England) [Category] COVID19(2023년), SARS, 변종, 치료제, [키워드] Abstract Admission age ambulatory patient Analysis Antiviral antiviral drug authority B.1.1.529 Case-control Charlson Comorbidity Index China Chinese clinical effectiveness Cohort Community Control COVID-19 outpatient Cox regression death Diagnosis diagnosis of SARS-CoV-2 Disease progression dominant Effectiveness glomerular filtration rate hazard Hong Kong hospitalisation HRs identify in both group In-hospital In-hospital death Infection intensive care Invasive mechanical ventilation less Logistic regression lower risk material median molnupiravir Mortality Nirmatrelvir non-hospitalised Odds ratio Older older patients outcome Outpatient Patient patients with COVID-19 primary analysis reduced risk Region Registered retrospective cohort risk Ritonavir SARS-CoV-2 SARS-COV-2 infection sensitivity analysis Sex supported the SARS-CoV-2 translation used data vaccination variant [DOI] 10.1016/S0140-6736(22)01586-0 PMC 바로가기
Estimation of biochemical factors affecting survival in intensive care COVID-19 patients undergoing chest CT scoring: A retrospective cross-sectional studyArticle Published on 2022-10-072022-11-16 Journal: Medicine [Category] 변종, [키워드] 95% CI Affect affecting age APACHE II APACHE II score approval biochemical Blood urea nitrogen changed Chest computed tomography Chest CT chest CT scan conducted Coronavirus disease 2019 COVID-19 COVID-19 patient COVID-19 patients Data analysis determine died estimation ethics committee Factor faculty females Follow-up greater Health ICU intensive care Invasive mechanical ventilation laboratory parameter males marker Mortality mortality rate no significant difference nonsurvivor nonsurvivors pandemic Patient PCR PCR test polymerase chain positive Prognosis ranged Respiratory disease Retrospective cross-sectional study significantly SPSS survival survivor symptomatic patient the mean the patient the WHO Transmission university variant was used were recorded widespread window Wuhan [DOI] 10.1097/MD.0000000000030407 PMC 바로가기